Table 5.
Results of the multivariate multinomial logistic regression showing the features available at onset that independently predict the clusters adopting a significance P value threshold of 0.001
| Feature | Prevalence, % | Group Versus Referencea | β | RR (eβ) | P Value |
|---|---|---|---|---|---|
| No. of alternative pathway abnormalitiesb | 45:12 | 4 | −2.3 | 0.10 | <0.001 |
| Serum C3c | 23:61 | 4 | −2.0 | 0.14 | <0.001 |
| Intramembranous highly electron-dense deposits | 16 | 3 | 3.8 | 44 | <0.001 |
| Glomerular C1q deposits ≥1+ | 38 | 2 | 3.2 | 25.2 | <0.001 |
Only associations with a P<0.001 are shown. RR, relative risk.
a
The group with the greatest number of patients (cluster 1) was taken as the reference group.
b
Abnormalities include the alleles with LPVs and C3NeFs; the prevalence rates of patients with one and two abnormalities are reported.
c
Serum C3 subdivided as normal (≥90 mg/dl), low (between ≥50 and <90 mg/dl), and very low (<50 mg/dl); the prevalence rates of patients with low and very low C3 are reported.