Table 1.

Summary statistics for the meta-analysis of urinary Mg²⁺-to-creatinine ratio

SNP	Effect Allele	Other Allele	Mean Effect Allele Frequency	Effect Size Discovery (SE)	P Value Discovery	Effect Size Replication (SE)	P Value Replication	Effect Size Combined Analysis (SE)	P Value Combined Analysis	Direction of Effects of Individual Cohorts	I2
rs35929	a	g	0.21	−0.112	5.57×10−6	−0.135	5.95×10−7	−0.1227	2.11×10−11	− − − − − − −	35.7
				(−0.025)		(−0.027)		(−0.183)
rs3824347	g	a	0.41	−0.109	3.61×10−8	−0.1125	2.02×10−6	−0.1103	4.38×10−13	− − − − − + −	7
				(−0.02)		(−0.024)		(−0.152)

The effect size sign for each individual cohort in the last but one column is represented by – or +. The cohort displaying a “-” for rs35929 is LBC1936, having an effect close to 0. The last column shows the I² value, representing the heterogeneity across cohorts.