Table 2.
FFA subtypes independently associated with complex lipid subclasses of TAGs, DAGs, and PEs using multiple linear regression models adjusted for age, sex, and race
| Complex Lipid Subclasses (Dependent Variable) | Independent FFA Associates | B | SEM | r | P Value |
|---|---|---|---|---|---|
| Short, low double-bond TAG | Length ≤ C-20 | −0.25 | 0.089 | −0.19 | <0.01 |
| Long, low double-bond TAG | Length ≤ C-20 | −0.754 | 0.128 | −0.58 | <0.001 |
| Long, low double-bond TAG | Length ≤ C-20 | 0.660 | 0.135 | 0.48 | <0.001 |
| Short, low double-bond DAG | Length ≤ C-20 | −0.221 | 0.089 | −0.17 | 0.01 |
| Intermediate-length, low double-bond PE | Length ≤ C-20 | −0.219 | 0.089 | −0.17 | 0.02 |
| Long PE | Length ≤ C-20 | 0.458 | 0.087 | 0.33 | <0.001 |
Short FFA is defined as ≤20 carbons, and long is defined as >20 carbons. Complex lipid subclasses as well as FFA cutoffs for acyl-chain length are defined by PCA. Acyl chain >20 carbons is indicated as >C-20, and acyl chain ≤20 is indicated as ≤C-20.