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. 2017 Oct 17;29(1):317–325. doi: 10.1681/ASN.2017060713

Table 2.

Secondary end points on the basis of the available patients at the end of the trial phase: high-GFR arm

End Point Supportive Care, n=54 Corticosteroid Monotherapy, n=55 P Value
Patients with Available Data, No. End Point Value, Mean±SD or No. (%) Patients with Available Data, No. End Point Value, Mean±SD or No. (%)
GFR decrease ≥30 ml/min per 1.73 m2 52 6 (12) 53 5 (9) 0.68
Onset of ESRD 52 5 (10) 53 1 (2) 0.16
Disappearance of microhematuria 38a 7 (18) 40a 19 (48) 0.02
Absolute GFR changes at month 36, ml/min per 1.73 m2 48 −3.78±13.41 52 −4.07±15.66 0.98
Mean annual change in the slope of the reciprocal of serum creatinine concentration, mg/dl 53 −0.02±0.06 52 −0.01±0.06 0.35
Urinary protein-to-creatinine ratio at month 12, g/g 47 0.79±0.74 41 0.5±0.52 0.01
Urinary protein-to-creatinine ratio at month 36, g/g 46 0.80±0.64 43 0.57±0.53 0.26
a

A total of 45 patients in the supportive care group and 50 patients in the corticosteroid monotherapy group had microhematuria at baseline.