Table 1.

Clinical characteristics in patients with tumor cell or lymphocyte PD-L1 expression

Variable	Overall		PD-L1
			PT-Infiltrating immune cell(+)			PT-tumor cell (+)			LNM-lymphocyte(+)			LNM-tumor cell(+)
	N	%	N	%	p	N	%	p	N	%	p	N	%	p
	101		31	30.69		26	25.74		54	53.46		41	40.59
Age, years					0.667			0.823			0.841			0.543
≤ 50	45	44.55	15	48.39		11	42.31		25	46.30		20	48.78
> 50	56	55.46	16	51.61		15	57.69		29	53.70		21	51.22
Menopausal Status					0.661			1			0.689			0.410
Post	60	59.41	17	54.84		15	57.69		31	57.41		22	53.66
Pre	41	40.59	14	45.16		11	42.31		23	42.59		19	46.34
Tumor size					1			0.816			0.541			0.149
≤ 2 cm	38	37.62	12	38.71		9	34.62		22	40.74		19	46.34
> 2 cm	63	62.38	19	61.29		17	65.38		32	59.26		22	53.66
Histological grade					0.031			0.130			1			0.175
II	28	27.72	4	12.90		4	15.38		15	27.78		8	19.51
III	73	72.28	27	87.10		22	84.62		39	72.22		33	80.49
Node status					0.198			0.545			0.623			0.280
pN1 (1–3 LNs)	52	51.49	19	61.29		16	61.54		30	55.55		25	61.98
pN2 (4–9 LNs)	29	28.71	9	29.03		6	23.08		15	27.78		10	24.39
pN3 (≥10 LNs)	20	19.80	3	9.68		4	15.38		9	16.67		6	14.63
TIL score(%)					0.020			0.001			0.399			0.042
0–10	60	59.41	12	38.71		7	26.92		32	59.26		21	51.22
11–20	22	21.78	10	32.26		10	38.46		14	25.93		14	34.15
≥ 21	19	18.81	9	29.03		9	34.62		8	14.81		6	14.63
Local recurrence					0.506			0.072			0.134			0.013
absence	89	88.12	26	83.87		20	76.92		45	83.33		32	78.05
presence	12	11.88	5	16.13		6	23.08		9	16.67		9	21.95
Distant metastasis					0.797			0.592			0.033			0.094
absence	78	77.23	23	74.19		19	73.08		37	68.52		28	68.29
Presence	23	22.77	8	25.81		7	26.92		17	31.48		13	31.71

Abbreviations: PD-L1 programmed cell death ligand 1, PT primary tumor, LNM lymph node metastasis, TIL tumor infiltrating lymphocyte

p-value of less than 0.05 was considered statistically significant