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. 2018 Jan 2;217(1):179–193. doi: 10.1083/jcb.201612147

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© 2018 Strauss et al.

This article is available under a Creative Commons License (Attribution 4.0 International, as described at https://creativecommons.org/licenses/by/4.0/).

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Figure 6. — Nuclear Cyclin B1 accelerates entry into mitosis. (A) The lengths of different phases of the cell cycle were quantified after injecting either PCNA alone (PCNA, green; three independent experiments), wild-type Cyclin B1 (mB1, blue; four independent experiments), or nuclear Cyclin B1 (B1NLS, red; five independent experiments). y axis shows time in minutes (mean; error bars represent ±SD of the mean) is shown for each of the genotypes: +/+ (wt), +/− (het), and −/− (ko). Numbers inside bars indicate number of divisions analyzed. (B) The greatest difference in timing between wild-type and nuclear Cyclin B1 was in G2 phase where nuclear Cyclin B1 reduced G2 length by ∼40% (P < 0.0001, two-sided t test; error bars: ±SD of the mean; ****, P < 0.0001).