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. 2018 Jan 2;217(1):211–230. doi: 10.1083/jcb.201704071

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© 2018 Izadi et al.

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Figure 8. — Cobl-like–mediated dendritic arborization relies on Abp1 and both proteins coincide at nascent branch induction sites. (A) MIPs of primary hippocampal neurons transfected with GFP-Cobl-like and Abp1 RNAi. Bars, 20 µm. (B–E) Quantitative analyses of indicated dendritic parameters addressing whether the Cobl-like gain-of-function phenotypes are Abp1-dependent. Data are mean ± SEM, one-way ANOVA plus Tukey’s post test (B–D) and two-way ANOVA plus Bonferroni’s post test (E). (F and G) Individual frames (MIPs) of 3D time lapse recordings of GFP-Cobl-like and Flag-mCherry-Abp1^Δflex in a dendrite of a hippocampal neuron. Labeling and heat map representation (G) are explained in Fig. 3. Bars, 2 µm. *, P < 0.05; **, P < 0.01; ***, P < 0.001.