Fig. 5.

OSS induces sustained associations of TβRs and integrins in ECs plated on FN, but only transient associations of these molecules in ECs plated on LM. ECs plated on FN or LM were kept under static conditions (C) or subjected to OSS (0.5 ± 4 dyn/cm²) for 1 h (a and c) or 24 h (b and d). The cells were lysed to determine the interaction of β1 (a and b) and β3 (c and d) integrins with TβRII and TβRI by using immunoprecipitation assay. Data are means ± SEM from three independent experiments. ^*P < 0.05 vs. static control cells