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. 2018 Jan 2;150(1):67–82. doi: 10.1085/jgp.201711895

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© 2018 Brown et al.

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Figure 1. — Auxiliary proteins regulate the gating properties of AMPARs. (A–C) Example electrophysiological responses from GluA2 (A; patch 150911p1), GluA2-γ2 (B; patch 151126p5), and GluA2 + CNIH-3 (C; patch 151109p4) evoked by 10 mM l-Glu (200 ms, holding potential = −60 mV) in the presence of 150 mM NaCl_(o). (D and E) Summary of the decay kinetics (D) and equilibrium currents (ss/pk ratio; E) for GluA2, GluA2-γ2, and GluA2 + CNIH-3. Data are means ± SEM. (F) Scatter plot showing the relationship between the decay kinetics (weighted τ) and the ss/pk ratio for each receptor complex.