Table 3. Spermine block rates in GluA2 receptors.
Receptor | Permeant blocker model | n | |||||||||
---|---|---|---|---|---|---|---|---|---|---|---|
kon | koff | kperm | Kd(0mV) | ||||||||
a (µM−1s−1) | b (mV) | c (s−1) | d (mV) | e (s−1) | f (mV) | (µM) | |||||
GluA2 | 29 | 113 | 156 | −19 | 32 | 20 | 6 | 7 | |||
SEM | 5 | 13 | 30 | 1 | 16 | 3 | 1 |
Block rate parameters were obtained by fitting the current relaxation after the voltage steps.