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. 2017 Dec 26;23:6121–6131. doi: 10.12659/MSM.907401

Figure 1.

Figure 1

Effects of pioglitazone or pioglitazone + PPAR-γ inhibitor GW9662 treatment on the atherosclerotic lesion area in ApoE−/− diabetic mice. (A–C) Representative Oil Red O staining images showing the atherosclerotic lesion area and quantitative analysis on the proportion of atherosclerotic lesions in aortic arch (A), thoracic aorta (B), and abdominal aorta (C) in ApoE−/− diabetic mice. * p<0.05. N=8 per group. (D) Quantitative analysis on the proportion of atherosclerotic lesions in whole aorta in ApoE−/− diabetic mice. * p<0.05. N=8 per group. C, control group; D, diabetic group; D + P, diabetic + pioglitazone group; D + P + G, diabetic + pioglitazone + GW9662 group.