Figure 6.

RNA editing modulates miRNA strand selection. (A) Spearman's correlation coefficient (rho) between the 5p/3p ratio and editing level for editing sites in 5p and 3p arms of the mature miRNAs were shown separately. (B) The comparison of the 5p/3p ratio of edited miRNAs between wild-type and Adarb1 knockout mice. We required that both 5p and 3p were covered by at least 30 reads and the 5p/3p ratio is between 0.01 and 100. The editing level difference between wild-type and Adarb1 knockout mice was shown in parentheses. (Error bars) SD. P-values were calculated using student t-test: (*) P < 0.05; (**) P < 0.01.