Table 1.
Characteristics of patients with SCCOP (N = 1008)
| Characteristic | No. (%) of patients | No. of patients with recurrence | 5-year recurrence rate | P valuea |
|---|---|---|---|---|
| No. of patients | 1008 (100) | 181 | 0.20 | |
| Age, years | ||||
| ≤57 | 621 (61.6) | 85 | 0.15 | < 0.0001 |
| > 57 | 387 (38.4) | 96 | 0.27 | |
| Sex | ||||
| Male | 872 (86.5) | 161 | 0.20 | 0.3110 |
| Female | 136 (13.5) | 20 | 0.19 | |
| Ethnicity | ||||
| Non-Hispanic white | 913 (90.6) | 146 | 0.17 | < 0.0001 |
| Other | 95 (9.4) | 35 | 0.41 | |
| Smoking | ||||
| Never | 388 (38.5) | 51 | 0.14 | 0.0004 |
| Ever | 620 (61.5) | 130 | 0.23 | |
| Alcohol use | ||||
| Never | 247 (24.5) | 26 | 0.10 | 0.0005 |
| Ever | 761 (75.5) | 155 | 0.23 | |
| Comorbidity | ||||
| None or mild | 913 (90.6) | 157 | 0.19 | 0.0370 |
| Moderate to severe | 95 (9.4) | 24 | 0.27 | |
| Index cancer stage | ||||
| 1 or 2 | 72 (7.1) | 11 | 0.19 | 0.5280 |
| 3 or 4 | 936 (92.9) | 170 | 0.20 | |
| Treatment | ||||
| X/XC/X/S | 947 (93.9) | 166 | 0.19 | 0.0030 |
| XC | 61 (6.1) | 15 | 0.32 | |
| HPV status | ||||
| HPV(+) | 324 | 45 | 0.12 | 0.0187 |
| HPV(-) | 51 | 10 | 0.21 | |
| HPV (not available) | 633 | 126 | 0.24 |
a
P: Log-rank test for DFS between the two groups.
X, radiotherapy
C, chemotherapy
S, surgery (for treatment purpose)