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. Author manuscript; available in PMC: 2018 Jan 2.
Published in final edited form as: ACS Biomater Sci Eng. 2017 Sep 28;3(12):3273–3282. doi: 10.1021/acsbiomaterials.7b00600

Figure 3.

Figure 3

Evaluation of gene expression changes induced by MCP-1 PAMs. Whole genome microarray analysis was performed on murine monocytes (WEHI.274.1) cultured with MCP-1 PAMs for 1 h and compared to PBS-treated samples on an Illumina BeadChip MouseWG-6 v2.0 expression array (n = 4). Out of 45 281 transcripts analyzed, 59 genes were differentially expressed between MCP-1 PAM vs PBS-treated groups and only Top3b and Rab3a showed decreased expression with FDR corrected p-value, q ≤0.05 and the fold change was ≥1.5.