Table 2.
Suggestive association signals (P<1×10−5) observed in a genome-wide association study (GWAS) of 6.3 million SNPs, 2000–2009 (n=5075)*
SNP identifier | Chr | Closest gene | Major allele | Minor allele | MAF | β† | SE | P |
rs1151814 | 1 | PARP1 | T | C | 0.10 | −0.16 | 0.03 | 2.0×10–6 |
rs9357354 | 6 | NCR2 | G | C | 0.17 | 0.13 | 0.03 | 1.4×10–6 |
rs75283006 | 8 | RBPMS-AS1 | A | G | 0.09 | 0.15 | 0.03 | 1.7×10–5 |
rs9537514 | 13 | PRR20 | G | T | 0.21 | 0.11 | 0.02 | 4.4×10–6 |
rs28790308 | 15 | ONECUT1 | C | G | 0.25 | −0.10 | 0.02 | 3.6×10–6 |
*GWAS was adjusted for sex, age, TL measurement type and batch effects.
†Association estimates are for the minor allele. The major allele is the reference allele.
GWAS, genome-wide association studies; MAF, minor allele frequency; TL, telomere length.