Figure 1.

Effects of quetiapine (15 mg/kg PO) administration on paw withdrawal frequency compared to the vehicle-treated group. The paclitaxel group only received paclitaxel (2 mg/kg IP) for five consecutive days, which resulted in neuropathic pain. The vehicle group was only treated with saline 0.9% solution and ’did not receive paclitaxel. The quetiapine+vehicle group received quetiapine (15 mg/kg PO) dissolved in a saline solution. The results are expressed as Mean±SEM, ###P<0.001 versus the vehicle group, n=8 in all groups