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Effect of quetiapine (5, 10, and 15 mg/kg PO) administration from 6th day to the 10th day on the expression of heat hyperalgesia. The paclitaxel group only received paclitaxel (2 mg/kg IP) for five consecutive days, which resulted in neuropathic pain. The vehicle group was only treated with a saline 0.9% solution and ’did not receive paclitaxel. The results are expressed as Mean±SEM, ###P<0.001 versus the vehicle group,***P<0.001 versus the paclitaxel group, n=8 in all groups
