Skip to main content
. Author manuscript; available in PMC: 2019 Jan 15.
Published in final edited form as: Int J Cancer. 2017 Sep 28;142(2):347–356. doi: 10.1002/ijc.31051

Table 2.

Clinical/Pathological Details of Potentially Clonal Cases

Case# Initial Histology Interval to 2nd
Primary		 2nd Tumor
Histology		 Outcome Clinical
Interpretation
8 T= 6.8cm, 22 positive nodes, extensive LVI, DCIS present, ER+/PR−/HER2− 1yr Inflammatory, 12 positive nodes, DCIS present, ER−/PR−/HER2− Distant metastases 11 months after second cancer Consistent with metastases
36 T>5cm, 19 positive nodes, extensive LVI, no DCIS, ER+/PR−/HER2− 3yrs T-diffuse, >5cm, 12 positive nodes, extensive LVI, no DCIS, ER+/PR−/HER2− NED years after initial diagnosis Consistent with metastases
48 Inflammatory, 5 positive nodes, no DCIS, ER+/PR+/HER2− Synchronous T= 5cm, 5 positive nodes, extensive LVI, no DCIS, ER+/PR+/HER2− Chest wall recurrence 12 yrs later Consistent with metastases
63 T= 1.0cm, 0/5 nodes, DCIS present, no LVI, ER+/PR+/HER2− Synchronous T= 1.8cm, 0/2 nodes, DCIS present, no LVI, ER+/PR+/HER2− NED 4 years 9months Independent primaries
67 T= 1.6cm, 0/1 nodes, DCIS present, no LVI, ER+/PR+/HER2− Synchronous T= 1.4cm, 1/3 positive nodes, DCIS present, no LVI, ER+/PR+/HER2− NED 3 years Independent primaries
75 T= 1.1cm, 0/1 nodes, DCIS present, no LVI, ER+/PR+/HER2− Synchronous T= 1.4cm, 0/1 nodes, DCIS present, no LVI, ER+/PR+/HER2− NED 1year Independent primaries

Abbreviation: DCIS, ductal carcinoma in situ; LVI, lymphovascular invasion; NED, no evidence of disease.