Table 2.

ROI Analyses: Positive associations between volume and abstinence duration

		Full Model (FRUs)			Slimmed Model (FRUs)			Interaction
	Region	Peak Coordinates	t value	pFWE	Peak Coordinates	t-value	pFWE	Peak Coordinates	t-value	pFWE
Alcohol	R Nucleus Accumbens	(14, 6, −8)	3.14	0.013
	L Nucleus Accumbens	(−16, 10, −15)	2.82	0.023
	R Putamen	(20, 15, 0)	3.94	0.010	(32, −18, −9)	3.43	0.034
	R Globus Pallidus	(16, 10, −3)	3.34	0.020
	R Amygdala	(27, 0, −18)	3.06	0.025	(27, −2, −15)	3.08	0.023
					(24, −9, −21)	2.75	0.048
	R Hippocamp				(33, −20, −9)	3.62	0.026
					(27, −16, −21)	3.43	0.043
					(32, −16, − 12)	3.39	0.047
Cocaine	L Nucleus Accumbens	(−12, 6, −15)	3.63	0.011
	R Nucleus Accumbens	(6, 10, −10)	3.78	0.011	(8, 12, −10)	3.05	0.028	(18, 6, −12)	3.59	0.006*
		(16, 6, −15)	3.68	0.01				(8, 12, −12)	3.12	0.017
	R Putamen			3				(28, 0, −6)	3.82	0.019
								(21, 6, −12)	3.75	0.022
	R Globus Pallidus							(27, 0, −6)	3.81	0.008
	R Hippocampus	(21, −6, −22)	4.88	0.015
	R Amygdala	(22, 0, −18)	4.95	0.003*				(27, −2, −14)	3.30	0.018
	R Medial OFC	(3, 10, −10)	5.59	0.003*				(6, 8, −14)	3.30	0.028
		(3, 18, −14)	4.03	0.039
	L DLPFC	(−30, 58, 6)	6.62	0.010
		(−16, 68, 0)	5.49	0.048
Cannabis	R Globus Pallidus							(22, 6, 2)	2.98	0.038
								(24, −2, 6)	2.98	0.039
	R Putamen							(24, 9, 0)	3.38	0.032

^*Significant after Bonferroni correction for multiple comparisons (p ≤ 0.006)