Table 5.
Whole-Brain Analyses: Regions of less volume in Former Regular Users compared to Former Light Users
| Region at Peak Coordinates | Other Regions in Cluster | Peak Coordinates | Cluster Size | Percent less volume in Cluster | |
|---|---|---|---|---|---|
| Alcohol | L Medial Orbitofrontal Cortex |
L Anterior Cingulate Gyrus | (−10, 52, −26) | 1858 | 18.5% |
| R Superior Lateral Occipital Cortex |
R Angular Gyrus R Middle Temporal Gyrus |
(45, −70, 27) | 973 | 13% | |
| R Middle Frontal Gyrus |
(36, 36, 26) | 1175 | 18.2% | ||
| R Precuneus | R Posterior Cingulate Gyrus L Precuneus L Posterior Cingulate Gyrus |
(8, −54, 22) | 1761 | 8.7% | |
| R Lingual Gyrus |
R Occipital Fusiform Gyrus R Lateral Occipital Cortex |
(15, −87, −3) | 1173 | 12.5% | |
| Cannabis | L Subcallosal Cortex |
R Anterior Cingulate Gyrus L Medial Orbitofrontal Cortex R Medial Orbitofrontal Cortex R Subcallosal Cortex |
(−4, 20, −16) | 3160 | 12.6% |