Figure 2.

Expected temporal distribution of Zika virus–related adverse pregnancy outcomes under different hypothetical outbreak scenarios, Brazil, April 2015–July 2017. Black lines indicate Zika cases; red lines indicate risk (APOs/1,000 births) for Zika-associated APO in subsequent weeks based on the 2 risk distributions in panel A. Dashed lines indicate timing of outbreaks: A) short, single-peaked outbreak; B) double-peaked outbreak; C) biennial epidemics (i.e., a seasonal endemic state). A population size of 1 million, reporting of 17% of Zika infections, and a 50% attack rate during a 4-year period were assumed. APO, adverse pregnancy outcome.