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. 2018 Feb;93(2):90–100. doi: 10.1124/mol.117.110569

TABLE 1 .

Slope of the relationship between log(L) and predicted log(EC50)

Results of linear regression of the value for log(EC50) on log(L) (third column), for various values of N (first column) and c (second column). The values were chosen to cover the range of proposed number of sites, and reported values for c for agonists acting on the GABAA receptor. The predictions were fit over a range of values for L that visually appear largely linear, as indicated in the fifth column. The fourth column gives the value of 1/N.

N c Slope 1/N Range of L
1 0.1 0.42 1.00 1–10
1 0.01 0.75 1.00 1–40
1 0.001 0.86 1.00 1–200
2 0.1 0.59 0.50 1–100
2 0.01 0.58 0.50 1–1000
2 0.001 0.55 0.50 1–1000
3 0.1 0.55 0.33 1–400
3 0.01 0.45 0.33 1–2000
3 0.001 0.44 0.33 1–2000
4 0.1 0.48 0.25 1–2000
4 0.01 0.39 0.25 1–2000
4 0.001 0.39 0.25 1–2000
5 0.1 0.42 0.20 1–1000
5 0.01 0.37 0.20 1–1000
5 0.001 0.37 0.20 1–1000