Table 1.
Drugs and frequency of DIC treatments
| Japan-Septic DIC study, 3,195 patients with sepsis treated in I | CU4 |
| Any DIC treatments | 47% |
| Antithrombin | 31% |
| Thrombomodulin | 27% |
| Co-administration of antithrombin and thrombomodulin | 16% |
| Protease inhibitors | 12% |
| Heparinoids | 5% |
| Japanese national administrative database, 14,324 patients with sepsis-induced DIC11 | |
| Antithrombin | 42% |
| Thrombomodulin | 44% |
| Protease inhibitors | 11% |
| Heparin | 30% |
| International sepsis registry, 12,881 patients with sepsis treated in ICU12 | |
| Antithrombin | 3% |
Abbreviations: DIC, disseminated intravascular coagulation; ICU, intensive care unit.