Table 1.
Participant Characteristics (Number of Patients = 95)
| M ± SD | Range | |
|---|---|---|
| Age at onset of PANS illness | 7.90 ± 3.44 | 2.21–17.7 |
| Flares per patient in dataset | ||
| Flares that received no NSAID treatment (Np = 82, Nf = 271) | 3.30 ± 2.77 | 1–13 |
| Flares that received early NSAID treatment (Np = 36, Nf = 43) | 1.19 ± 0.58 | 1–4 |
| Flares that received prophylactic NSAIDs (Np = 39, Nf = 76) | 1.95 ± 1.10 | 1–5 |
| n (%) | ||
|---|---|---|
| Male | 58/95 (61%) | |
| Obsessive-compulsive disorder | 85/95 (89%) | |
| Eating restrictiona | 49/94 (52%) | |
| Anxiety | 92/95 (97%) | |
| Mood dysregulationb | 93/95 (98%) | |
| Irritability/oppositionality/aggression | 89/95 (94%) | |
| Behavioral regressiona | 71/94 (76%) | |
| Academic deteriorationa | 64/91 (70%) | |
| Sensory or motor symptoms | 91/95 (96%) | |
| Somatic symptoms | 92/95 (97%) |
a
Some missing data: eating restriction and behavioral regression, n = 1. Academic deterioration, n = 4.
b
Mood dysregulation, including depression and/or emotional lability.
PANS, Pediatric Acute-onset Neuropsychiatric Syndrome; NSAIDs, nonsteroidal anti-inflammatory drugs; NP, number of patients; NF, number of flares.