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Salubrinal (Sal) significantly reduced the activation of nuclear factor kappa B (NFκB) in vitro following endoplasmic reticulum (ER) stress induction with tunicamycin (TUN). A significant difference between TUN and control was seen for NFκB activation in NG-108 cells following treatment (q = 4.432; p < 0.05). Sal significantly reduced the increase by TUN (t = 4.101; p < 0.05). *p < 0.05 for Control versus TUN groups. #p < 0.05 for TUN versus TUN + Sal groups.
