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. 2017 Dec 1;24(12):1243–1253. doi: 10.1089/cmb.2017.0100

FIG. 2.

FIG. 2.

Optimal value selection of the parameter IC threshold. (A) The IC thresholds are selected from 6 to 8.5 in steps of 0.5. For each IC threshold value, a ChIP dataset (wgEncodeSydhTfbsHepg2Nrf1IggrabPk) is tested 16 times. Every time, we choose the minimal E-value of all meeting matches between the predicted motifs and the motif NRF1. Then, we draw them in broken lines. (B) For each IC threshold value, we calculate the average E-value of 16 minimal E-values and draw these average E-values in broken lines. (C) For each IC threshold value, we compute the mean-square deviation of the 16 minimum E-values and plot them in the same way. IC, information content.