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. Author manuscript; available in PMC: 2018 Nov 8.
Published in final edited form as: Cell Host Microbe. 2017 Nov 8;22(5):697–704.e4. doi: 10.1016/j.chom.2017.10.007

Figure 3. SFB Induce Th17 Cells of the Gut-Lung Axis.

Figure 3

(A) Percentage of lung and splenic Th17 and Th1 cells from littermates of SFB+ K/BxN mice treated with vancomycin or left untreated (n = 8–9/group, two assays combined).

(B) Percentage of Th17 and Th1 cells from Th17- or Th1-polarized KRN T cell cultures before transfer. Representative plots of five assays are shown.

(C) The retention of transferred Th17 polarizing cells in recipient spleen or lung from the experiments in (B) is shown and calculated as percentage of preserved Th17 cells: the post-transfer Th17 percentage in spleen or lung were normalized to the starting Th17 percentage in the polarization culture of each of five experiments (n = 5–8/group, five assays combined). Similar calculations were used for Th1 cells.

(D) Transcript fold induction of CCL20 (n = 6–10/group, two assays combined).