Table 2.

Clinical Outcomes: Summary of responses and survival. NED = No Evident Disease by examination and chest x- ray for at least 8 weeks followed by negative scans. The table provides median and range of data on all 87 patients for: time to NED, the % of patients achieving NED for greater than 2 months, and the % of patients with a cumulative duration of NED of 2, 3 and 5 years. The table also presents median and range of overall and disease-free survival from entry at different times. Because some patients relapsed after being free of disease for protracted periods, the % of subjects surviving free of disease for 1 to 5 years after entry is less than the cumulative duration of disease free periods. Also a few disease-free patients were lost to follow up.

Melanoma Clinical Outcomes: Summary Tables
	Time to			NED Duration in months
Frequency and durability of responses	Median	Range	% all pts	Median	Range	NED 1 yr	NED 2 yr	NED 3 yr	NED ≥ 5 yr
At least 2 completely regressed met	4 mo	0–46	72%
NED >2 months (CR)	15	0–48	38%	59	2–334	31%	28%	24%	20%
NED when last seen			25%	100	6–348
57 pts (66%) reached stage IV			11% of stage IV	100	5–334
				Survival in months
Survival				Median	Range	Surv 1 yr	Surv 2 yr	Surv 3 yr	Surv ≥ 5 yr
All pts overall survival from entry				28.5	4–348	70%	54%	43%	29%
All pts survival from entry, disease free			25%	100	6–348	23%	23%	23%	20%
Progres. dis. 54 pts, never NED : survival to death or chemo				18	3 to 75	56%	30%	20%	9%