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. 2017 Nov 7;7(2):e1393133. doi: 10.1080/2162402X.2017.1393133

Table 4.

Differences of immune expression in preoperative biopsy and tumor.

  Biopsy (median (range)) Tumor (median (range)) p
CD3+ stroma 387.3 (85.7–850.3) 252.5 (94.7–719.3) n.s.
CD3+ epithel 9.0 (0.0–34.0) 3.0 (0–23) n.s.
CD3+/MIB1+ stroma 4.8 (0.3–29.0) 2.3 (0–19) n.s.
CD3+/MIB1+ epithel 0.5 (0.0–3.0) 0.0 (0–4) n.s.
CD8+ stroma 65.0 (25.0–156.7) 103.5 (21.7–253.7) 0.036
CD8+ epithel 3.0 (0–17) 2.0 (0–21) n.s.
GrzB+/CD8+ stroma 26.7 (12.7–79.7) 38.5 (0–167.3) 0.011
GrzB+/CD8+ epithel 2.0 (0–12) 2.0 (0–19) n.s.
GrzB/CD8//CD8 stroma 0.60 (0–0.71) 0.46 (0.27–0.59) 0.007
GrzB/CD8//CD8 epithel 0.85 (0–1) 0.77 (0–1) n.s.

Abbreviations: n.s.: not significant (P>0.05); CD: cluster of differentiation; MIB: mindbomb E3 ubiquitin protein ligase 1; GrzB: granzyme B.