Table 1. Kinetic parameters of NDM-1 and L209F enzymes.

Substrates	NDM-1			L209F
	Km (μM)	kcat (s-1)	kcat/Km (μM-1 s-1)	Km (μM)	kcat (s-1)	kcat/Km (μM-1 s-1)
Imipenem	35±1	64	1.83	33±5	0.55	0.017
Meropenem	80±2	75	0.94	50±1	0.86	0.017
Biapenem	120±4	30	0.25	109±4	0.52	0.0047
Cefazolin	20±1	42	2.1	16±2	0.34	0.021
Loracarbef	40±2	42	1.05	20±3	0.78	0.039
Benzylpenicillin	250±10	105	0.42	7±0,5	1.00	0.140
Carbenicillin	285±5	108	0.38	20±3	1.40	0.070