Fig 7. TFV insensitivity of moDC-to-PBMC transmission is dependent on infectious dose of NL4-3.
(A) PBMCs with or without moDCs were infected with varying doses of NL4-3. Frequency of p24+ T cells was measured by flow cytometry. (B, C) PBMCs with or without moDCs were infected with varying doses of NL4-3 in the presence or absence of 10 μM of TFV and drug insensitivity (Tx) (B) and fold difference between the Tx values were measured (C). Mean ± s.e.m (η = 2 donors). Data is representative of two independent experiments (A-C).