Table 1. Selected genes for testing DNA microarray outcomes in quantitative real-time PCR.
| Gene name | Systematic name | P-value | Fold change | Protein name | Function |
|---|---|---|---|---|---|
| MMP1 | NM_002421 | 0,00007 | 1,6 | Interstitial collagenase | Cleaves collagens of types I, II, and III |
| PLAT | NM_000930 | 0,003 | 1,4 | Tissue-type plasminogen activator | Role in tissue remodeling |
| SLIT2 | NM_004787 | 0,003 | 1,3 | Slit homolog 2 protein | Molecular guidance in cellular migration |
| ARHGAP22 | NM_021226 | 0,004 | 1,3 | Rho GTPase-activating protein 22 | Regulates endothelial cell capillary tube formation |
| A2M | NM_000014 | 0,00005 | -2,1 | Alpha-2-macroglobulin | Inhibitor of proteinases |
| CORO1B | NM_020441 | 0,001 | -1,4 | Coronin-1B | Regulates leading edge dynamics and cell motility |
| SHC1 | NM_183001 | 0,002 | -1,5 | SHC-transforming protein 1 | Signaling adapter |
| FN1 | NM_054034 | 0,005 | -1,4 | Fibronectin | Involved in cell adhesion and motility |
The individuated genes took part to biological processes where MSC could have a role in the regenerative support after QMR stimulation.