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. 2018 Jan 2;13(1):e0190205. doi: 10.1371/journal.pone.0190205

Fig 1. A comparison of amyloid beta in cortex and dentate gyrus area of hippocampus and NeuN positive cell in arcuate nucleus between the triple transgenic (3xtg-AD) and control.

Fig 1

A. Mice with the 3xtg-AD genes (top) showed amyloid beta under fluorescent microscopy compared to control (bottom). Representative image of cortex (left) and dentate gyrus area of hippocampus(Right) showed amyloid beta congregation around neurons in the 3xtg-AD and few in the control. B. Representation of arcuate nucleus neuron population (NeuN positive) from the control, 3xtg-AD at 20 weeks of age. Arc: Arcuate nucleus of hypothalamus; VMH: Ventromedial nucleus of the hypothalamus; 3V: third ventricle, scale bars represent 200 μM.