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. 2018 Jan 2;13(1):e0190354. doi: 10.1371/journal.pone.0190354

Table 1. Characteristics of included studies.

Reference Age, years Patient number (magnesium/ control) Surgery Local anesthetics used for caudal anesthesia Amount of local anesthetics Scoring tool for pain Definition of the end of analgesic duration
Birbicer 2007 [18] 2–10 23/37 Inguinal hernia repair,
orchidopexy,
circumcision
0.25% ropivacaine 0.5 mL/kg POPS, CHEOPS Not defined
Elshal 2009 [19] 4–10 20/20 Hypospadias surgery 0.25% ropivacaine 0.5 mL/kg (1 mL/kg in Discussion) OPS First dose of analgesia administered (OPS ≥4)
Kim 2014 [20] 2–6 39/38 Inguinal hernia repair 0.15% ropivacaine 1 mL/kg PPPM First oral acetaminophen administration after surgery (when PPPM was ≥6)
Yousef 2014 [21] 1–6 35/35 Inguinal hernia repair 0.15% ropivacaine 1.5 mL/kg CHEOPS, FLACC Time when FLACC and CHEOP was ≥4
Sridhar 2017 [16] 3–12 32/32 Infraumbilical surgery 0.2% ropivacaine 0.5 mL/kg MOPS The time from caudal block to acetaminophen administration (MOPS >4)
Askar 2017 [17] 1–6 30/30 Inguinal orchidopexy, distal hypospadias surgery, inguinal hernia repair 0.25% bupivacaine 1 mL/kg FLACC The time from caudal block to the first analgesic administration (FLACC > 7)

POPS, Paediatric Objective Pain Score; CHEOPS, Children’s Hospital of Eastern Ontario Pain Scale; OPS, Objective Pain Scale; PPPM, Parent’s Postoperative Pain Measurement; FLACC, Faces Legs Activity Cry Consolability tool; MOPS, Modified Objective Pain Score