Fig 4.

Off-target effects of the treatment of F. gigantica NEJs with SOD (A), σGST (B), Cat B2 (C) and Cat B1-B3 (D) specific dsRNA trigger on non-targeted mRNA transcripts at 72 h post-RNAi. Results are presented as the mean ± standard error (SE) of the unit value of 2^−ΔΔCt from three independent experiments. P values of ≤0.05 were considered significant. Experiments were repeated ≥3 times. Significant differences between dsRNA treated and untreated control worms are indicated (*, P<0.05; **, P<0.01; ***, P<0.001).