Table 2. Dermal changes in the infected footpad of BALB/c mice in treated and control groups.

Group	Parasite	Plasma cell	Granuloma	Inflammation
G1-1	N.S *	-	-	0–1 (limited)
G1-2	2(+)	-	-	0–1 (limited)
G2-1	N.S	-	-	0–1 (limited)
G2-2	1(+)	-	-	1–2 (limited)
G3-1	2(+)	-	-	2(+) (limited)
G3-2	2(+)	-	-	3(+) (diffuse)
G4-1	2(+)	-	-	2(+) (limited)
G4-2	2(+)	-	IG**	2(+) (limited)
G5-1	4(+)	+	IG	4(+) (diffuse)
G5-2	4(+)	+	IG	4(+) (diffuse

Two mice were euthanized at six weeks post infection and their lesions were fixed in formalin for histopathological analysis. G1: folded HNP1, G2: pcDNA-HNP-EGFP, G3: pcDNA-EGFP, G4: AmB, G5: non-treated.

*N.S: Not Seen

**IG: Immature Granuloma