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. 2018 Jan 2;12(1):014102. doi: 10.1063/1.5019728

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Copyright © 2018 Author(s)

Published by AIP Publishing.

1932-1058/2018/12(1)/014102/19/$30.00

PMC Copyright notice

FIG. 3. — Highly metastatic prostate cancer cells (PC3, n = 94; CL2, n = 103) have similar nucleus fluidity to moderately metastatic prostate cancer cells (DU145, n = 91), non-metastatic cells (LNCaP, n = 47), and normal prostate epithelial cells (RWPE-1, n = 83). (a) Fluidity α cumulative distribution function (CDF) and (b) mean α (±SE). Highly metastatic prostate cancer cells have a lower nucleus stiffness than moderately metastatic and normal cells. (c) Stiffness 1/A CDF with the abscissa truncated to emphasize differences and (d) mean 1/A (±SE). (e) Nucleus fluidity and (f) stiffness do not depend on the nucleus radius R_N.