. Author manuscript; available in PMC: 2019 Jan 1.

Published in final edited form as: Kidney Int. 2017 Aug 31;93(1):252–259. doi: 10.1016/j.kint.2017.06.028

Table 2. Adjusted Hazard Ratios for Incident Chronic Kidney Disease by Quartile of Plasma Galectin-3.

Model	Quartile of Plasma Level of Galectin-3 (Range, ng/mL)				P-value

	Quartile 1 (4.4-12.0)	Quartile 2 (12.1-14.1)	Quartile 3 (14.2-16.7)	Quartile 4 (16.8-91.6)
1^a	1 [Ref]	1.25 (1.09-1.44)	1.53 (1.32-1.77)	2.22 (1.89-2.60)	<0.001
2^b	1 [Ref]	1.17 (1.01-1.34)	1.35 (1.16-1.56)	1.84 (1.57-2.17)	<0.001
3^c	1 [Ref]	1.17 (1.01-1.34)	1.34 (1.16-1.55)	1.81 (1.54-2.13)	<0.001
4^d	1 [Ref]	1.15 (1.00-1.32)	1.31 (1.13-1.51)	1.75 (1.49-2.06)	<0.001

Model 1: adjusted for age, sex, race-center, education level, physical activity, smoking status, body mass index, systolic blood pressure, anti-hypertensive medication use, history of cardiovascular disease, diabetes status, fasting blood glucose, rs4644

Model 2: Model 1 + estimated glomerular filtration rate-creatinine

Model 3: Model 2 + urine albumin-to-creatinine ratio

Model 4: Model 3 + troponin T, N-terminal pro B-type natriuretic peptide