Skip to main content
. Author manuscript; available in PMC: 2019 Jan 1.
Published in final edited form as: Kidney Int. 2017 Aug 23;93(1):128–146. doi: 10.1016/j.kint.2017.06.008

Table 6.

Statistically over-represented Gene Ontology Biological Process terms among transcripts with altered abundance on Day 2 of vasopressin-escape.ˆ

GO Biological Process Term* Number of Genes Fold Enrichment False Discovery Rate (%) P (Fisher Exact)
cell cycle process 44 6.6 4.10E-20 4.60E-24
cell cycle 49 5.7 5.40E-20 7.10E-24
cell division 22 8 4.30E-10 3.80E-14
chromosome segregation 15 15.1 6.40E-10 2.60E-14
organelle organization 47 2.6 2.40E-06 7.50E-10
microtubule-based process 19 5.2 2.90E-05 4.30E-09
nitrogen compound metabolic process 62 1.6 1.40E-01 7.00E-05
negative regulation of biological process 50 1.7 3.00E-01 1.50E-04
DNA packaging 9 5.2 4.10E-01 6.00E-05
cellular response to stimulus 27 2.1 5.30E-01 2.00E-04
positive regulation of biological process 55 1.6 6.30E-01 3.30E-04
ˆ

“Altered transcripts” were those with Benjamini-Hochberg FDR-adjusted P value < 0.1.

*

Analysis used DAVID Functional Annotation tools (see (Methods) to identify all terms with False Discovery Rate (FDR) < 1%.

“Fold Enrichment” is the fraction of genes with the given GO term in the “regulated” list divided by the fraction of genes in full list (“regulated” + “unregulated”) with that term.