Table 6.
GO Biological Process Term* | Number of Genes | Fold Enrichment† | False Discovery Rate (%) | P (Fisher Exact) |
---|---|---|---|---|
cell cycle process | 44 | 6.6 | 4.10E-20 | 4.60E-24 |
cell cycle | 49 | 5.7 | 5.40E-20 | 7.10E-24 |
cell division | 22 | 8 | 4.30E-10 | 3.80E-14 |
chromosome segregation | 15 | 15.1 | 6.40E-10 | 2.60E-14 |
organelle organization | 47 | 2.6 | 2.40E-06 | 7.50E-10 |
microtubule-based process | 19 | 5.2 | 2.90E-05 | 4.30E-09 |
nitrogen compound metabolic process | 62 | 1.6 | 1.40E-01 | 7.00E-05 |
negative regulation of biological process | 50 | 1.7 | 3.00E-01 | 1.50E-04 |
DNA packaging | 9 | 5.2 | 4.10E-01 | 6.00E-05 |
cellular response to stimulus | 27 | 2.1 | 5.30E-01 | 2.00E-04 |
positive regulation of biological process | 55 | 1.6 | 6.30E-01 | 3.30E-04 |
“Altered transcripts” were those with Benjamini-Hochberg FDR-adjusted P value < 0.1.
Analysis used DAVID Functional Annotation tools (see (Methods) to identify all terms with False Discovery Rate (FDR) < 1%.
“Fold Enrichment” is the fraction of genes with the given GO term in the “regulated” list divided by the fraction of genes in full list (“regulated” + “unregulated”) with that term.