Table 7.
Altered transcripts in CCD on Day 2 of vasopressin-escape with Gene Ontology Biological Process term ‘Cell Cycle’*
| Gene Symbol | Annotation | Log2(Escape/Control) | Padj (Benjamini-Hochberg) |
|---|---|---|---|
| Mlf1 | myeloid leukemia factor 1 | 4.17 | 2.52E-13 |
| Tacc3 | transforming, acidic coiled-coil containing protein 3 | 3.57 | 2.39E-12 |
| Tubb5 | tubulin, beta 5 | 1.90 | 3.33E-12 |
| Cenpf | centromere protein F | 3.75 | 4.17E-12 |
| E2f1 | E2F TF 1 | 3.68 | 2.80E-11 |
| Uhrf1 | ubiquitin-like with PHD and ring finger domains 1 | 3.43 | 1.80E-08 |
| Ube2c | ubiquitin-conjugating enzyme E2C | 2.82 | 2.58E-08 |
| Aurkb | aurora kinase B | 2.64 | 2.34E-07 |
| Kifc1 | kinesin family member C1 | 2.02 | 2.54E-07 |
| Pole | polymerase (DNA directed), epsilon | 2.79 | 3.28E-07 |
| Fancd2 | Fanconi anemia, complementation group D2 | 2.96 | 1.92E-06 |
| Dscc1 | defective in sister chromatid cohesion 1 | 2.16 | 4.72E-06 |
| Spc25 | SPC25, NDC80 kinetochore complex component | 2.43 | 7.80E-06 |
| Cdca8 | cell division cycle associated 8 | 2.61 | 2.02E-05 |
| Plk1 | polo-like kinase 1 (Drosophila) | 2.46 | 4.09E-05 |
| Mcm6 | minichromosome maintenance complex component 6 | 1.83 | 6.77E-05 |
| Id4 | inhibitor of DNA binding 4 | −2.15 | 7.41E-05 |
| Brca1 | breast cancer 1 | 2.52 | 1.93E-04 |
| Ncaph | non-SMC condensin I complex, subunit H | 1.66 | 3.33E-04 |
| Aurka | aurora kinase A | 1.61 | 1.33E-03 |
| Racgap1 | Rac GTPase-activating protein 1 | 1.87 | 1.45E-03 |
| Mad2l1 | MAD2 (mitotic arrest deficient, homolog)-like 1 | 1.98 | 2.44E-03 |
| Stmn1 | stathmin 1 | 1.56 | 3.30E-03 |
| Cdc25b | cell division cycle 25 homolog B (S. pombe) | 1.57 | 3.61E-03 |
| Birc5 | baculoviral IAP repeat-containing 5 | 1.78 | 3.82E-03 |
| Cdc5l | CDC5 cell division cycle 5-like (S. pombe) | 1.38 | 4.31E-03 |
| Pttg1 | pituitary tumor-transforming 1 | 2.09 | 4.89E-03 |
| Cdc20 | cell division cycle 20 homolog (S. cerevisiae) | 1.64 | 4.97E-03 |
| Kif2c | kinesin family member 2C | 2.07 | 5.96E-03 |
| Katna1 | katanin p60 (ATPase-containing) subunit A1 | 1.49 | 7.35E-03 |
| Wee1 | wee 1 homolog (S. pombe) | 1.29 | 7.35E-03 |
| Kif18a | kinesin family member 18A | 1.98 | 7.83E-03 |
| Haus4 | HAUS augmin-like complex, subunit 4 | 1.19 | 7.84E-03 |
| Pola1 | polymerase (DNA directed), alpha 1 | 1.86 | 9.08E-03 |
| Cenpa | centromere protein A | 1.82 | 9.69E-03 |
| Nusap1 | nucleolar and spindle associated protein 1 | 1.65 | 9.69E-03 |
| Trip13 | thyroid hormone receptor interactor 13 | 1.68 | 9.69E-03 |
| Msh5 | mutS homolog 5 | 1.57 | 1.17E-02 |
| Ccna2 | cyclin A2 | 1.82 | 1.49E-02 |
| Cdca3 | cell division cycle associated 3 | 1.57 | 3.32E-02 |
| Rad51c | Rad51 homolog c | 1.55 | 3.62E-02 |
| Calm2 | calmodulin 2 | 1.21 | 3.95E-02 |
| Cdkn1b | cyclin-dependent kinase inhibitor 1B | −1.16 | 4.57E-02 |
| Txnl4b | thioredoxin-like 4B | 1.42 | 4.72E-02 |
| Mdm2 | Mdm2 p53 binding protein | −1.16 | 4.73E-02 |
| Timeless | timeless homolog | 1.57 | 5.35E-02 |
| Dlgap5 | discs, large homolog-associated protein 5 | 1.47 | 5.36E-02 |
| Nuf2 | NDC80 kinetochore complex component | 1.54 | 7.70E-02 |
| Ska2 | family with sequence similarity 33, member A | 1.49 | 9.01E-02 |
*
Includes all transcripts for “cell cycle” Gene Ontology term in Table 6.