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Disulfiram dose- and time-dependently decreased NE tissue levels in the striatum. Mean ± SEM NE levels (pg/mg tissue) in the frontal cortex (A) and striatum (B) 120 min after pre-treatment with vehicle or disulfiram (10 or 50 mg/kg). Data for the 30-min pre-treatment interval are given in the bottom panels for the frontal cortex (C) and striatum (D). *p < 0.05 compared to vehicle. Sample size was n = 8 for all groups
