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. Author manuscript; available in PMC: 2019 Jan 1.
Published in final edited form as: Psychopharmacology (Berl). 2017 Oct 30;235(1):23–35. doi: 10.1007/s00213-017-4744-0

Table 3.

Effect of disulfiram on other measures of the rGT at either the 30- or 120-min pre-treatment time for the optimal (n = 29, 120 min; n = 27, 30 min) and suboptimal (n = 10, 120 min; n = 12, 30 min) groups. Data presented are mean ± SEM

Variable Group Doses (mg/kg)
Vehicle 10 25 50 75 100
30-min pre-treatment
Trials Optimal** 106 ± 6.9 113 ± 6.7 115 ± 6.4 112 ± 5.7 115 ± 5.6 111 ± 5.7
Suboptimal 75 ± 3.4 71 ± 3.6 73 ± 2.3 76 ± 3.4 77 ± 5.5 67 ± 4.5
% premature Optimal** 11 ± 1.5 11 ± 1.6 11 ± 1.8 11 ± 1.6 10 ± 1.4 10 ± 1.6
Suboptimal 16 ± 2.4 19 ± 2.1 17 ± 1.9 16 ± 2 17 ± 2.3 17 ± 3.6
Reward perseverative Optimal 0.01 ± 0.004 0.001 ± 0.001 0.02 ± 0.01 0.005 ± 0.002 0.007 ± 0.002 0.013 ± 0.01
Suboptimal 0.015 ± 0.01 0.04 ± 0.02 0.002 ± 0.001 0.02 ± .01 0.03 ± 0.02 0.03 ± 0.03
Punishment perseverative Optimal 0.052 ± 0.01 0.047 ± 0.01 0.055 ± 0.01 0.048 ± 0.004 0.049 ± 0.01 0.05 ± 0.01
Suboptimal 0.048 ± 0.01 0.042 ± 0.01 0.050 ± 0.01 0.049 ± 0.01 0.051 ± 0.01 0.048 ± 0.01
Choice latency Optimal 1.13 ± 0.14 1.21 ± .19 1.26 ± 0.20 1.26 ± 0.20 1.27 ± 0.18 1.29 ± 0.19
Suboptimal 1.0 ± 0.15 0.86 ± 0.12 1.09 ± 0.16 1.1 ± 0.14 1.06 ± 0.16 1.27 ± 0.20
Collect latency Optimal 3.08 ± 1.22 1.44 ± 0.06 3.05 ± 1.60 1.46 ± 0.06 1.49 ± 0.08 1.95 ± 0.36
Suboptimal 1.28 ± 0.07 1.26 ± 0.09 1.24 ± 0.08 1.24 ± 0.07 1.20 ± 0.06 2.89 ± 1.60
% omissions Optimal 0.82 ± 0.36 1.15 ± 0.61 1.36 ± 0.55 1.58 ± 0.81 1.34 ± 0.54 1.12 ± 0.34
Suboptimal 1.40 ± 0.98 3.6 ± 2.48 1.12 ± 0.63 0.73 ± 0.28 1.05 ± 0.35 2.81 ± 2.46
120-min pre-treatment
Trials Optimal** 113 ± 7.88 115 ± 7.64 108 ± 5.25 112 ± 5.62 104 ± 4.31 107 ± 6.79
Suboptimal 67 +± 6.37 71 ± 5.13 81 ± 9.23 77 ± 6.9 73 ± 5.7 75 ± 5.51
% premature Optimal** 13 ± 1.6 12 ± 1.4 11 ± 1.2 11 ± 1.2 14 ± 1.4 14 ± 1.7
Suboptimal 20 ± 3.8 17 ± 2.8 20 ± 2.4 18 ± 2.7 20 ± 2.9 16 ± 2.8
Reward perseverative Optimal 0.45 ± 0.13 0.38 ± 0.11 0.45 ± 0.13 0.46 ± 0.15 0.64 ± 0.18 0.41 ± 0.11
Suboptimal 0.02 ± 0.01 0.05 ± 0.02 0.03 ± 0.02 0.03 ± 0.01 0.02 ± 0.01 0.02 ± 0.01
Punishment perseverative Optimal 0.056 ± 0.01 0.049 ± 0.01 0.049 ± 0.01 0.052 ± 0.004 0.052 ± 0.01 0.049 ± 0.005
Suboptimal 0.051 ± 0.01 0.063 ± 0.01 0.053 ± 0.01 0.058 ± 0.01 0.050 ± 0.01 0.058 ± 0.01
Choice latency Optimal 0.95 ± 0.12 0.92 ± 0.11 0.96 ± 0.12 0.99 ± 0.15 0.95 ± 0.12 1.01 ± 0.15
Suboptimal 1.36 ± 0.16 1.33 ± 0.21 1.08 ± 0.12 1.04 ± 0.06 1.02 ± 0.12 1.26 ± 0.13
Collect latency Optimal 1.74 ± 0.43 1.35 ± 0.05 1.38 ± 0.07 1.33 ± 0.05 1.32 ± 0.05 1.31 ± 0.05
Suboptimal 1.37 ± 1.13 1.36 ± 0.13 1.34 ± 0.09 1.36 ± 0.10 1.34 ± 0.09 1.37 ± 0.11
% omissions Optimal 1.55 ± 0.79 0.85 ± 0.33 0.89 ± 0.37 1.47 ± 0.91 0.77 ± 0.38 1.10 ± 0.58
Suboptimal 1.14 ± 0.38 0.42 ± 0.22 0.78 ± 0.48 0.36 ± 0.19 1.32 ± 0.89 1.08 ± 0.57
**

A significant effect of group (p < 0.05)