Table 1.
IPA results from comparison between cell lines and native tumors
Ingenuity Canonical Pathways | -log(p-value) | Ratio | z-score |
---|---|---|---|
Mouse | |||
Hepatic Fibrosis / Hepatic Stellate Cell Activation | 9.93E00 | 5.15E-01 | |
Agranulocyte Adhesion and Diapedesis | 9.45E00 | 5.48E-01 | |
Calcium Signaling | 8.73E00 | 5.1E-01 | -5.060 |
Cellular Effects of Sildenafil (Viagra) | 7.07E00 | 5.28E-01 | |
Crosstalk between Dendritic Cells and Natural Killer Cells | 5.72E00 | 5.93E-01 | |
B Cell Development | 5.58E00 | 7.73E-01 | |
Leukocyte Extravasation Signaling | 5.36E00 | 4.44E-01 | -1.697 |
Granulocyte Adhesion and Diapedesis | 5.09E00 | 4.78E-01 | |
Eicosanoid Signaling | 4.4E00 | 5.81E-01 | -0.905 |
T Helper Cell Differentiation | 4.35E00 | 5.62E-01 | |
Human | |||
Oxidative Phosphorylation | 2.39E01 | 6.67E-01 | |
Mitochondrial Dysfunction | 1.97E01 | 5.22E-01 | |
phagosome maturation | 6.19E00 | 4.04E-01 | |
CD28 Signaling in T Helper Cells | 5.09E00 | 3.89E-01 | |
Fcγ Receptor-mediated Phagocytosis in Macrophages and Monocytes | 4.46E00 | 3.84E-01 | -0.870 |
Complement System | 4.23E00 | 5.36E-01 | 1.508 |
Dendritic Cell Maturation | 3.97E00 | 3.36E-01 | |
Crosstalk between Dendritic Cells and Natural Killer Cells | 3.33E00 | 3.93E-01 | |
Allograft Rejection Signaling | 3.15E00 | 4.81E-01 | |
Altered T Cell and B Cell Signaling in Rheumatoid Arthritis | 2.93E00 | 4E-01 | |
Combined mouse and human | |||
CD28 Signaling in T Helper Cells | 3.52E00 | 1.63E-01 | |
B Cell Development | 3.49E00 | 4.17E-01 | |
Serine Biosynthesis | 3.16E00 | 7.5E-01 | |
Dendritic Cell Maturation | 2.93E00 | 1.38E-01 | |
Oxidative Phosphorylation | 2.87E00 | 1.54E-01 | |
Superpathway of Serine and Glycine Biosynthesis I | 2.5E00 | 5E-01 | |
Complement System | 2.47E00 | 2.63E-01 | 0.000 |
Phagosome maturation | 2.42E00 | 1.36E-01 | |
FcγRIIB Signaling in B Lymphocytes | 2.38E00 | 1.89E-01 | 1.134 |
PKCθ Signaling in T Lymphocytes | 2.38E00 | 1.35E-01 | 2.714 |