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. 2017 Apr 13;10(1-3):1–7. doi: 10.1007/s12307-017-0192-y

Table 1.

IPA results from comparison between cell lines and native tumors

Ingenuity Canonical Pathways -log(p-value) Ratio z-score
Mouse
 Hepatic Fibrosis / Hepatic Stellate Cell Activation 9.93E00 5.15E-01
 Agranulocyte Adhesion and Diapedesis 9.45E00 5.48E-01
 Calcium Signaling 8.73E00 5.1E-01 -5.060
 Cellular Effects of Sildenafil (Viagra) 7.07E00 5.28E-01
 Crosstalk between Dendritic Cells and Natural Killer Cells 5.72E00 5.93E-01
 B Cell Development 5.58E00 7.73E-01
 Leukocyte Extravasation Signaling 5.36E00 4.44E-01 -1.697
 Granulocyte Adhesion and Diapedesis 5.09E00 4.78E-01
 Eicosanoid Signaling 4.4E00 5.81E-01 -0.905
 T Helper Cell Differentiation 4.35E00 5.62E-01
Human
 Oxidative Phosphorylation 2.39E01 6.67E-01
 Mitochondrial Dysfunction 1.97E01 5.22E-01
 phagosome maturation 6.19E00 4.04E-01
 CD28 Signaling in T Helper Cells 5.09E00 3.89E-01
 Fcγ Receptor-mediated Phagocytosis in Macrophages and Monocytes 4.46E00 3.84E-01 -0.870
 Complement System 4.23E00 5.36E-01 1.508
 Dendritic Cell Maturation 3.97E00 3.36E-01
 Crosstalk between Dendritic Cells and Natural Killer Cells 3.33E00 3.93E-01
 Allograft Rejection Signaling 3.15E00 4.81E-01
 Altered T Cell and B Cell Signaling in Rheumatoid Arthritis 2.93E00 4E-01
Combined mouse and human
 CD28 Signaling in T Helper Cells 3.52E00 1.63E-01
 B Cell Development 3.49E00 4.17E-01
 Serine Biosynthesis 3.16E00 7.5E-01
 Dendritic Cell Maturation 2.93E00 1.38E-01
 Oxidative Phosphorylation 2.87E00 1.54E-01
 Superpathway of Serine and Glycine Biosynthesis I 2.5E00 5E-01
 Complement System 2.47E00 2.63E-01 0.000
 Phagosome maturation 2.42E00 1.36E-01
 FcγRIIB Signaling in B Lymphocytes 2.38E00 1.89E-01 1.134
 PKCθ Signaling in T Lymphocytes 2.38E00 1.35E-01 2.714