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. 2017 Nov 24;10(1-3):95–103. doi: 10.1007/s12307-017-0202-0

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© The Author(s) 2017

Open Access This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made.

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Fig. 5 — Differnetial impact of SR11302 at different points of tumor development: a-c There is no significant difference in the tumor number of cells that were grown on a petri dish (2D) when treated with SR11302 for 4 days for H1299 (p = 0.25, A), A549 (p = 0.65, B), and H460 (p = 0.44, C) cells. d-f When same number of CTC from the 4D model seeded with H1299 (D), A549 (E) or H460 (F) treated with or without SR11302 were plated on the petri dish for 4 days, there was significantly less viable cells with treatment for H1299 (p = 0.01), A549 (p = 0.008) and H460 (p = 0.04)