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. 2017 Dec;6(6):715–725. doi: 10.21037/gs.2017.11.02

Table 1. Study characteristics. Details of each study with regards to: country where study was conducted, length of study, sample size (n), main quality improvement (QI) technique used and outcome of study.

References Country and length n Main intervention stated Outcomes
Al-Hakim et al., 2012 Australia, 5 months 31 Lean principles (included time and motion principles, process charts, motion economy) Preventable disruption accounts for 25% increase in surgical time
Attarian et al., 2013 USA, 3 years DNS Six Sigma principles (included DMAIC) OT start increased from <60% to >90%;
average turnover time decreased by 25 minutes;
average number of cases per OT increased by 29%
Berber et al., 2002 USA, DNS 33 Time and efficiency analysis technique Surgical steps that took statistically longer were identified
Berber et al., 2001 USA, ?4 years (stated 1994–1997) 48 Time and efficiency analysis technique Longer operating times identified in specific clinical situations
Cima et al., 2011 USA, 6 months Pre-implementation:
specialty 1, 735;
specialty 2, 1,740;
specialty 3, 1,685
Lean and Six Sigma principles (included process mapping and value stream mapping) Statistically significant improvement in on-time starts, reduction in non-operative time, increase in percentage of OTs closed at 5 p.m., reduction in staff overtime
Post-implementation:
specialty 1, 2,430;
specialty 2, 2,430;
specialty 3, 1,907
Collar et al., 2012 USA, 18 months Before: 35; after: 55 Lean principles Significantly shorter mean turnover time and turnaround time;
improved staff morale after implementation; surgical trainee education unchanged
Damle et al., 2016 USA, 7 months Before: 107; after: 110 Lean principles Statistically significant decrease in mean colonoscopy time by 10%;
overall colonoscopy unit capacity increased from 39.6 to 43.6 per day
Harewood et al., 2008 Ireland, 5 weeks 400 Time-motion approach Efficiency quotient increased with four separate interventions by up to 63.3%
Lee et al., 2008 Israel, 4 years (stated 2005–2008) 100 Harvard Business School Model Mean operative time for both unilateral and bilateral DIEP flap breast reconstruction decreased, with no change in complication rate; statistically significant improvement in prophylactic heparin administration;
antibiotic administration and redosing of antibiotics trended upwards;
improved interdisciplinary communication, transition guidelines, and enhanced efficiency
Marsh et al., 2016 UK, 12 months 163 Process mapping Increased overall efficiency in DIEP flap breast reconstruction, achieving three operations in one theatre in 1 day, compared to one operation previously
McLaughlin et al., 2014 USA, DNS 124 (total across two different groups) Time-driven activity-based costing (included process mapping) Pilot study which identified average cost capacities for personnel in theatre
Minekus et al., 2005 Netherlands, DNS 40 Time-action analysis Identified large variations in duration of shoulder joint replacement operations, tasks for team members, and approach used;
identified factors which influenced operation (the prosthesis, the surgical approach, surgeon experience, and patient condition);
main limitations identified as repeated actions and waiting time
Schwarz et al., 2011 Germany, ?3 years (stated 2008–2010) Before: 42; after: 75 Value stream mapping (VSM) Decrease in mean throughput time in colonoscopy unit, with corresponding decrease in patient waiting time by 23%
Tebbetts, 2002 USA, 5 years Before: group 1, 16; group 2, 16;
after: 627
Time and motion study principles Anaesthetic, operative and postanaesthetic care times decreased significantly
Toro et al., 2015 USA, DNS 30 Analysis of a stepwise technique Identified: mean operative time as the step with the least time variance, longest step, step with greatest time variance
Warner et al., 2015 USA, 12 months 127 VSM, DMAIC, Lean Six Sigma principles, process redesign Reduced mean technical costs of endovascular aneurysm repair by 10%, reduced instrument use by 39%
Warner et al., 2013 USA, 1 year and 9 weeks (stated follow-up period to 1 year from implementation) Before: 62; after: 926 Lean Six Sigma principles 32% increase in first case on-time starts, with a sustained 86% on-time start rate at 1-year follow-up

DMAIC, define, measure, analyze, improve and control; DNS, did not state; OT, operating theatres; DIEP, deep inferior epigastric perforator.