Figure 1.

Odds ratios and minor allele frequencies in controls of 113 non-MHC AS-associated variants identified in Ellinghaus et al.²² Each bar and dot represents a GWS variant. The variants are labelled by nearby genes. The red and green bars respectively represent odds ratio of AS-associated variants from AS-only case–control analyses, and analyses leveraging pleiotropy. Black dot represents minor allele frequency in healthy controls. The blue line indicates 5% minor allele frequency.