Table 3. Number of associations reported in published GWAS of other polygenic diseases, which were based on a similar or smaller sample size than the largest asthma GWAS published.

Disease	N cases	N controls	N Total	N of independent associations in discovery GWAS (P<5x10−8)	PMID	Disease prevalence	NCP for a SNP with h2=0.05%
Atopic dermatitis	18900	84166	103066	21	26482879	20%	24
Asthma	28399	128843	157242	27	27182965	15%	40
Type 2 diabetes	26676	132532	159208	42	28566273	5%	52
Schizophrenia	36989	113075	150064	128	25056061	1%	102
Rheumatoid arthritis	29880	73758	103638	101	24390342	1%	77

Abbreviations: PMID, PubMed identifier; NCP: non-centrality parameter (which reflects power); h2: heritability.

All studies are based on the analysis of 1000 Genome Project SNPs imputed from GWAS arrays (not including fine-mapping arrays).