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Ex vivo growth of human umbilical cord mesenchymal stem cells (HUCMSCs) alone, co-cultured with ARPE19 cells, or with condition ARPE19 medium. (a) Phase-contrast and fluorescence microscopic images of HUCMSCs grown on Matrigel after 7 days with or without co-culture with ARPE19 or with conditioned ARPE19 medium. Scale bar=1000 μm (left panel) and 100 μm (middle and right panels). (b) HUCMSC colony numbers in microscopic field. ***P<0.001 compared with the group without co-culture.
