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. 2018 Jan;59(1):147–153. doi: 10.2967/jnumed.117.193169

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FIGURE 4. — Patient with neuroblastoma for follow-up evaluation and possible therapy with ¹³¹I-MIBG. ¹²³I-MIBG images (A, anterior; B, posterior) show foci of suspicious activity in skull, lumbar vertebra, right and left acetabula, and right femur (black arrows). Patient underwent imaging with 162 MBq of ¹⁸F-MFBG a wk later. Whole-body maximum-intensity-projection scans with ¹⁸F-MFBG (C and D) show all lesions seen on ¹²³I-MIBG scan but with greater contrast and clarity (black arrows). In addition, several lesions are seen on ¹⁸F-MFBG scan only (red arrows) that are not visible on ¹²³I-MIBG images. For example, fused PET/CT transaxial ¹⁸F-MFBG image (F) shows intense uptake in left acetabulum (red arrow), suspicious for disease, that is not seen on ¹²³I-MIBG SPECT/CT fused transaxial image (E). Also, left iliac bone lesions are clearly avid on ¹⁸F-MFBG (H) vs. ¹²³I-MIBG imaging (G).